Connective Tissue Growth Factor in Idiopathic Pulmonary Fibrosis: Breaking the Bridge

Connective Tissue Growth Factor in Idiopathic Pulmonary Fibrosis: Breaking the Bridge

CTGF is upregulated in patients with idiopathic pulmonary fibrosis (IPF), characterized by the deposition of a pathological extracellular matrix (ECM). Additionally, many omics studies confirmed that aberrant cellular senescence-associated mitochondria dysfunction and metabolic reprogramming had bee...

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Bibliographic Details
Main Authors: Wiwin Is Effendi, Tatsuya Nagano
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
CTGF
pro-fibrotic
mitochondria dysfunction
metabolic dysregulation
senescence
chronic respiratory diseases
Online Access:https://www.mdpi.com/1422-0067/23/11/6064

Internet

https://www.mdpi.com/1422-0067/23/11/6064

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