Alport Syndrome: Clinical Spectrum and Therapeutic Advances

Alport Syndrome: Clinical Spectrum and Therapeutic Advances

Alport syndrome is a hereditary disorder characterized by kidney disease, ocular abnormalities, and sensorineural hearing loss. Work in understanding the cause of Alport syndrome and the molecular composition of the glomerular basement membrane ultimately led to the identification of COL4A3, COL4A4...

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Bibliographic Details
Main Authors: Vanessa De Gregorio, Emine Bilge Caparali, Azadeh Shojaei, Samantha Ricardo, Moumita Barua
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Kidney Medicine
Subjects:
Alport syndrome
ACEi
angiotensin-converting enzyme inhibitor
gene editing
glomerular basement membrane
investigational therapeutics
Online Access:http://www.sciencedirect.com/science/article/pii/S2590059523000407

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http://www.sciencedirect.com/science/article/pii/S2590059523000407

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