Fronto-striatal dopamine D2 receptor availability is associated with cognitive variability in older individuals with low dopamine integrity

Abstract Within-person, moment-to-moment, variability in behavior increases with advancing adult age, potentially reflecting the influence of reduced structural and neurochemical brain integrity, especially that of the dopaminergic system. We examined the role of dopamine D2 receptor (D2DR) availabi...

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Bibliographic Details
Main Authors: Saana M. Korkki, Goran Papenberg, Nina Karalija, Douglas D. Garrett, Katrine Riklund, Martin Lövdén, Ulman Lindenberger, Lars Nyberg, Lars Bäckman
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-00106-y