Interactions of alpha-synuclein with membranes in Parkinson's disease: Mechanisms and therapeutic strategies

Parkinson's disease (PD), the second most common neurodegenerative disease worldwide, is marked by the presence of Lewy bodies and Lewy neurites, neuronal lesions containing large amounts of the synaptic protein alpha-synuclein (αS). While the underlying mechanisms of disease progression in PD...

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Bibliographic Details
Main Authors: Baoyi Li, Ulf Dettmer
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996124002468