RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal

RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal

Summary: Lipid droplets (LDs) are dynamic organelles that undergo dynamic changes in response to changing cellular conditions. During nutrient depletion, LD numbers increase to protect cells against toxic fatty acids generated through autophagy and provide fuel for beta-oxidation. However, the preci...

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Bibliographic Details
Main Authors: Syed S. Hussain, Tuyet-Minh Tran, Timothy B. Ware, Melissa A. Luse, Christopher T. Prevost, Ashley N. Ferguson, Jennifer A. Kashatus, Ku-Lung Hsu, David F. Kashatus
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Cell Reports
Subjects:
RalA
PLD1
lipid droplets
nutrient withdrawal
Perilipin 3
phosphatidic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721008688

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http://www.sciencedirect.com/science/article/pii/S2211124721008688

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