Machine learning-based algorithms applied to drug prescriptions and other healthcare services in the Sicilian claims database to identify acromegaly as a model for the earlier diagnosis of rare diseases

Abstract Acromegaly is a rare disease characterized by a diagnostic delay ranging from 5 to 10 years from the symptoms’ onset. The aim of this study was to develop and internally validate machine-learning algorithms to identify a combination of variables for the early diagnosis of acromegaly. This r...

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Bibliographic Details
Main Authors: Salvatore Crisafulli, Andrea Fontana, Luca L’Abbate, Giacomo Vitturi, Alessia Cozzolino, Daniele Gianfrilli, Maria Cristina De Martino, Beatrice Amico, Carlo Combi, Gianluca Trifirò
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-56240-w