The regional sequestration of heterochromatin structural proteins is critical to form and maintain silent chromatin

The regional sequestration of heterochromatin structural proteins is critical to form and maintain silent chromatin

Abstract Budding yeast Saccharomyces cerevisiae and fission yeast Schizosaccharomyces pombe are good models for heterochromatin study. In S. pombe, H3K9 methylation and Swi6, an ortholog of mammalian HP1, lead to heterochromatin formation. However, S. cerevisiae does not have known epigenetic silenc...

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Bibliographic Details
Main Authors: Junsoo Oh, Soojin Yeom, Jiyeon Park, Jung-Shin Lee
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Epigenetics & Chromatin
Subjects:
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Heterochromatin structural proteins
SIR complex
Swi6
Online Access:https://doi.org/10.1186/s13072-022-00435-w

Internet

https://doi.org/10.1186/s13072-022-00435-w

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