Dietary fasting and time-restricted eating in Huntington’s disease: therapeutic potential and underlying mechanisms

Abstract Huntington's disease (HD) is a devastating neurodegenerative disorder caused by aggregation of the mutant huntingtin (mHTT) protein, resulting from a CAG repeat expansion in the huntingtin gene HTT. HD is characterized by a variety of debilitating symptoms including involuntary movemen...

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Bibliographic Details
Main Authors: Russell G. Wells, Lee E. Neilson, Andrew W. McHill, Amie L. Hiller
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Translational Neurodegeneration
Subjects:
Online Access:https://doi.org/10.1186/s40035-024-00406-z