Microbial biotransformation to obtain stilbene methylglucoside with GPR119 agonistic activity

Microbial biotransformation to obtain stilbene methylglucoside with GPR119 agonistic activity

IntroductionLimitation of pharmaceutical application of resveratrol (RSV) and piceatannol (PIC) continue to exist, there is a need to obtain the superior analogs of two stilbenes with promoted activity, stability, and bioavailability. Microbial transformation has been suggested as a common and effic...

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Bibliographic Details
Main Authors: Yu Peng, Yi Huan, Jing-Jing Chen, Tian-Jiao Chen, Lei Lei, Jin-Ling Yang, Zhu-Fang Shen, Ting Gong, Ping Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Microbiology
Subjects:
stilbenes
microbial transformation
Beauveria bassiana
methylglucosylation
GPR119 agonist
insulin secretion
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1148513/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2023.1148513/full

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