The TRIM37 variants in Mulibrey nanism patients paralyze follicular helper T cell differentiation

Abstract The Mulibrey (Muscle–liver–brain–eye) nanism caused by loss-of-function variants in TRIM37 gene is an autosomal recessive disorder characterized by severe growth failure and constrictive pericarditis. These patients also suffer from severe respiratory infections, co-incident with an increas...

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Bibliographic Details
Main Authors: Wangpeng Gu, Jia Zhang, Qing Li, Yaguang Zhang, Xuan Lin, Bingbing Wu, Qi Yin, Jinqiao Sun, Yulan Lu, Xiaoyu Sun, Caiwei Jia, Chuanyin Li, Yu Zhang, Meng Wang, Xidi Yin, Su Wang, Jiefang Xu, Ran Wang, Songling Zhu, Shipeng Cheng, Shuangfeng Chen, Lian Liu, Lin Zhu, Chenghua Yan, Chunyan Yi, Xuezhen Li, Qiaoshi Lian, Guomei Lin, Zhiyang Ling, Liyan Ma, Min Zhou, Kuanlin Xiao, Haiming Wei, Ronggui Hu, Wenhao Zhou, Lilin Ye, Haikun Wang, Jinsong Li, Bing Sun
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-023-00561-z