A robust internal control for high-precision DNA methylation analyses by droplet digital PCR

A robust internal control for high-precision DNA methylation analyses by droplet digital PCR

Abstract Background Droplet digital PCR (ddPCR) allows absolute quantification of nucleic acids and has potential for improved non-invasive detection of DNA methylation. For increased precision of the methylation analysis, we aimed to develop a robust internal control for use in methylation-specific...

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Bibliographic Details
Main Authors: Heidi D. Pharo, Kim Andresen, Kaja C. G. Berg, Ragnhild A. Lothe, Marine Jeanmougin, Guro E. Lind
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Clinical Epigenetics
Subjects:
Digital PCR
Internal control
Methylation
Normalization
PoDCall
4Plex
Online Access:http://link.springer.com/article/10.1186/s13148-018-0456-5

Internet

http://link.springer.com/article/10.1186/s13148-018-0456-5

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