A robust internal control for high-precision DNA methylation analyses by droplet digital PCR
Abstract Background Droplet digital PCR (ddPCR) allows absolute quantification of nucleic acids and has potential for improved non-invasive detection of DNA methylation. For increased precision of the methylation analysis, we aimed to develop a robust internal control for use in methylation-specific...
Main Authors: | Heidi D. Pharo, Kim Andresen, Kaja C. G. Berg, Ragnhild A. Lothe, Marine Jeanmougin, Guro E. Lind |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-02-01
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Series: | Clinical Epigenetics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13148-018-0456-5 |
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