Three-dimensional wide-field fluorescence microscopy for transcranial mapping of cortical microcirculation
A 3D wide-field fluorescence microscopy method is introduced based on optical astigmatism combined with fluorescence source localization. It enables transcranial cortical microcirculation mapping in murine brain with high spatiotemporal resolution.
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-35733-0 |