Detection of Microsatellite Instability in Colorectal Cancer Patients With a Plasma-Based Real-Time PCR Analysis

Detection of Microsatellite Instability in Colorectal Cancer Patients With a Plasma-Based Real-Time PCR Analysis

A microsatellite instability (MSI) test is crucial for screening for HNPCC (Hereditary nonpolyposis colorectal cancer; Lynch syndrome) and optimization of colorectal cancer (CRC) treatment. Mismatch repair (MMR) deficiency is a predictor for good response of immune checkpoint inhibitors in various m...

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Bibliographic Details
Main Authors: Namjoo Kim, Sung Min Kim, Beom Jae Lee, Byung il Choi, Hee Sook Yoon, Sang Hee Kang, Seung Han Kim, Moon Kyung Joo, Jong-Jae Park, Chungyeul Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Pharmacology
Subjects:
microsatellite instability
real-time PCR
colorectal cancer
mismatch repair
liquid biopsy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.758830/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.758830/full

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