Melatonin inhibits bladder tumorigenesis by suppressing PPARγ/ENO1-mediated glycolysis

Abstract Melatonin is a well-known natural hormone, which shows a potential anticancer effect in many human cancers. Bladder cancer (BLCA) is one of the most malignant human cancers in the world. Chemoresistance is an increasingly prominent phenomenon that presents an obstacle to the clinical treatm...

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Bibliographic Details
Main Authors: Dexin Shen, Zhao Deng, Wei Liu, Fenfang Zhou, Yayun Fang, Danni Shan, Gang Wang, Kaiyu Qian, Mengxue Yu, Yi Zhang, Lingao Ju, Yu Xiao, Xinghuan Wang
Format: Article
Language:English
Published: Nature Publishing Group 2023-04-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05770-8