Succinate utilisation by Salmonella is inhibited by multiple regulatory systems.

Succinate is a potent immune signalling molecule that is present in the mammalian gut and within macrophages. Both of these infection niches are colonised by the pathogenic bacterium Salmonella enterica serovar Typhimurium during infection. Succinate is a C4-dicarboyxlate that can serve as a source...

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Bibliographic Details
Main Authors: Nicolas Wenner, Xiaojun Zhu, Will P M Rowe, Kristian Händler, Jay C D Hinton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-03-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011142&type=printable