Benzyl isothiocyanate improves the prognosis of Aspergillus fumigatus keratitis by reducing fungal load and inhibiting Mincle signal pathway

Benzyl isothiocyanate improves the prognosis of Aspergillus fumigatus keratitis by reducing fungal load and inhibiting Mincle signal pathway

Aspergillus fumigatus keratitis is a potential blinding disease associated with A. fumigatus invasion and excessive inflammatory response. Benzyl isothiocyanate (BITC) is a secondary metabolite with broad antibacterial and anti-inflammatory activity extracted from cruciferous species. However, the r...

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Bibliographic Details
Main Authors: Wendan Yi, Lingwen Gu, Yuwei Wang, Jing Lin, Lina Zhang, Qian Wang, Weilin Diao, Yinghe Qi, Menghui Chi, Min Yin, Cui Li, Guiqiu Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Microbiology
Subjects:
benzyl isothiocyanate
Aspergillus fumigatus keratitis
antifungal
anti-inflammatory
Mincle
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1119568/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1119568/full

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