A phase II multicenter randomized study to evaluate the safety and efficacy of combining thermotherapy and a short course of miltefosine for the treatment of uncomplicated cutaneous leishmaniasis in the New World.

A phase II multicenter randomized study to evaluate the safety and efficacy of combining thermotherapy and a short course of miltefosine for the treatment of uncomplicated cutaneous leishmaniasis in the New World.

<h4>Background</h4>Systemic pentavalent antimonials, mainly meglumine antimoniate, continue to be the first-choice drugs for treatment of cutaneous leishmaniasis (CL) despite their toxicity, difficulty of administration and high cost. In the search for therapeutic alternatives, combining...

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Bibliographic Details
Main Authors: Liliana López, Braulio Valencia, Fiorela Alvarez, Ana Pilar Ramos, Alejandro Llanos-Cuentas, Juan Echevarria, Iván Vélez, Marina Boni, Joelle Rode, Juliana Quintero, Alejandra Jiménez, Yulied Tabares, Claudia Méndez, Byron Arana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0010238

Internet

https://doi.org/10.1371/journal.pntd.0010238

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