Dissecting the RecA-(In)dependent Response to Mitomycin C in <i>Mycobacterium tuberculosis</i> Using Transcriptional Profiling and Proteomics Analyses

Dissecting the RecA-(In)dependent Response to Mitomycin C in <i>Mycobacterium tuberculosis</i> Using Transcriptional Profiling and Proteomics Analyses

Mycobacteria exploit at least two independent global systems in response to DNA damage: the LexA/RecA-dependent SOS response and the PafBC-regulated pathway. Intracellular pathogens, such as <i>Mycobacterium tuberculosis</i>, are exposed to oxidative and nitrosative stress during the cou...

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Bibliographic Details
Main Authors: Anna Brzostek, Przemysław Płociński, Alina Minias, Aneta Ciszewska, Filip Gąsior, Jakub Pawełczyk, Bożena Dziadek, Marcin Słomka, Jarosław Dziadek
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cells
Subjects:
DNA damage repair
SOS response
tuberculosis
Online Access:https://www.mdpi.com/2073-4409/10/5/1168

Internet

https://www.mdpi.com/2073-4409/10/5/1168

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