Reversal of aging-associated increase in myelopoiesis and expression of alarmins by angiotensin-(1–7)

Abstract Aging is associated with chronic systemic inflammation largely due to increased myelopoiesis, which in turn increases risk for vascular disease. We have previously shown evidence for the therapeutic potential of Angiotensin-(1–7) (Ang-(1–7)) in reversing vasoreparative dysfunction in aging....

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Bibliographic Details
Main Authors: Kishore Chittimalli, Jesmin Jahan, Anil Sakamuri, Hope Weyrick, Wink Winkle, Steven Adkins, Stefan W. Vetter, Yagna P. R. Jarajapu
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-29853-w