Rapamycin Attenuates Acute Seizure-induced Astrocyte Injury in Mice in Vivo

Abstract Astrocytes have been implicated in epileptogenesis and seizure-induced brain injury. Pathological studies reveal a variety of structural abnormalities in astrocytes, such as vacuolization and astrogliosis. While in vivo imaging methods have demonstrated rapid changes in astrocytes under a v...

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Bibliographic Details
Main Authors: Dongjun Guo, Jia Zou, Michael Wong
Format: Article
Language:English
Published: Nature Portfolio 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03032-0