Preventive Vitamin A Supplementation Improves Striatal Function in 6-Hydroxydopamine Hemiparkinsonian Rats

Preventive Vitamin A Supplementation Improves Striatal Function in 6-Hydroxydopamine Hemiparkinsonian Rats

BackgroundThe mechanisms leading to a loss of dopaminergic (DA) neurons from the substantia nigra pars compacta (SNc) in Parkinson's disease (PD) have multifactorial origins. In this context, nutrition is currently investigated as a modifiable environmental factor for the prevention of PD. In p...

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Bibliographic Details
Main Authors: Anaïs Marie, Julien Leroy, Morgane Darricau, Serge Alfos, Veronique De Smedt-Peyrusse, Emmanuel Richard, Sylvie Vancassel, Clementine Bosch-Bouju
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Nutrition
Subjects:
vitamin A
dopamine
Parkinson's disease
6-hydroxydopamine (6-OHDA)
aldehyde dehydrogenase ALDH1A1
substantia nigra pars compacta (SNc)
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.811843/full

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https://www.frontiersin.org/articles/10.3389/fnut.2022.811843/full

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