CRISPR-based tools for targeted genetic manipulation in pathogenic Sporothrix species

CRISPR-based tools for targeted genetic manipulation in pathogenic Sporothrix species

ABSTRACT Sporothrix brasiliensis is an emerging fungal pathogen frequently associated with zoonotic transmission of sporotrichosis by contaminated cats. Within 25 years, the disease has spread not only throughout Brazil but now to neighboring countries in Latin America. Thermo-dimorphism, melanin, g...

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Bibliographic Details
Main Authors: Remi Hatinguais, Ian Leaves, Gordon D. Brown, Alistair J. P. Brown, Matthias Brock, Roberta Peres da Silva
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:Microbiology Spectrum
Subjects:
Sporothrix
DHN-melanin
pks1
ku80
CRISPR/Cas9
Online Access:https://journals.asm.org/doi/10.1128/spectrum.05078-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.05078-22

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