Identification of exosomal miR-484 role in reprogramming mitochondrial metabolism in pancreatic cancer through Wnt/MAPK axis control

Identification of exosomal miR-484 role in reprogramming mitochondrial metabolism in pancreatic cancer through Wnt/MAPK axis control

The microRNAs (miRNAs) are potent regulators of tumorigenesis in various cancers, especially pancreatic cancer. The abnormal expression of miRNAs can be observed in tumor cells. Noteworthy, miRNAs could be transferred by exosomes as small extracellular vesicles in regulation of carcinogenesis. This...

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Bibliographic Details
Main Authors: Tianyu Lin, Xiaofan Pu, Senhao Zhou, Zhengze Huang, Qi Chen, Yiyin Zhang, Qijiang Mao, Yuelong Liang, Guoping Ding
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Pharmacological Research
Subjects:
Pancreatic cancer
MiR-484
Exosomes
Mesenchymal stem cells
Mitochondria
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661823003365

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http://www.sciencedirect.com/science/article/pii/S1043661823003365

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