Association of MTHFR C677T polymorphism with risk of preterm birth in Indian mothers: a case–control study

Abstract Background Since MTHFR is the key enzyme in folate metabolism, its reduction can lead to hyperhomocysteinemia, which can have a negative impact on pregnancy outcome. Moreover, MTHFR polymorphism has also been linked with oxidative stress and genotoxicity. Identifying its ethnicity-specific...

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Bibliographic Details
Main Authors: Pratibha Rathod, Ajesh Desai, Divya Chandel
Format: Article
Language:English
Published: SpringerOpen 2023-01-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
Online Access:https://doi.org/10.1186/s43042-023-00385-2