Mycobacterium tuberculosis SatS is a chaperone for the SecA2 protein export pathway

The SecA2 protein export system is critical for the virulence of Mycobacterium tuberculosis. However, the mechanism of this export pathway remains unclear. Through a screen for suppressors of a secA2 mutant, we identified a new player in the mycobacterial SecA2 pathway that we named SatS for SecA2 (...

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Bibliographic Details
Main Authors: Brittany K Miller, Ryan Hughes, Lauren S Ligon, Nathan W Rigel, Seidu Malik, Brandon R Anjuwon-Foster, James C Sacchettini, Miriam Braunstein
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/40063