HIV DNA Set Point is Rapidly Established in Acute HIV Infection and Dramatically Reduced by Early ART

HIV DNA Set Point is Rapidly Established in Acute HIV Infection and Dramatically Reduced by Early ART

HIV DNA is a marker of HIV persistence that predicts HIV progression and remission, but its kinetics in early acute HIV infection (AHI) is poorly understood. We longitudinally measured the frequency of peripheral blood mononuclear cells harboring total and integrated HIV DNA in 19 untreated and 71 t...

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Bibliographic Details
Main Authors: Jintanat Ananworanich, Nicolas Chomont, Leigh Ann Eller, Eugene Kroon, Sodsai Tovanabutra, Meera Bose, Martin Nau, James L.K. Fletcher, Somporn Tipsuk, Claire Vandergeeten, Robert J. O'Connell, Suteeraporn Pinyakorn, Nelson Michael, Nittaya Phanuphak, Merlin L. Robb
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:EBioMedicine
Subjects:
Acute HIV infection
Art
HIV DNA
Reservoir
Persistence
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416303309

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http://www.sciencedirect.com/science/article/pii/S2352396416303309

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