Virally encoded interleukin-6 facilitates KSHV replication in monocytes and induction of dysfunctional macrophages.

Virally encoded interleukin-6 facilitates KSHV replication in monocytes and induction of dysfunctional macrophages.

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Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic double-stranded DNA virus and the etiologic agent of Kaposi's sarcoma and hyperinflammatory lymphoproliferative disorders. Understanding the mechanism by which KSHV increases the infected cell population is crucial for curing K...

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Bibliographic Details
Main Authors: Michiko Shimoda, Tomoki Inagaki, Ryan R Davis, Alexander Merleev, Clifford G Tepper, Emanual Maverakis, Yoshihiro Izumiya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011703

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https://doi.org/10.1371/journal.ppat.1011703

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