NISNet3D: three-dimensional nuclear synthesis and instance segmentation for fluorescence microscopy images

Abstract The primary step in tissue cytometry is the automated distinction of individual cells (segmentation). Since cell borders are seldom labeled, cells are generally segmented by their nuclei. While tools have been developed for segmenting nuclei in two dimensions, segmentation of nuclei in thre...

Full description

Bibliographic Details
Main Authors: Liming Wu, Alain Chen, Paul Salama, Seth Winfree, Kenneth W. Dunn, Edward J. Delp
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-36243-9