Synergistic effect of immune checkpoint blockade and anti-angiogenesis in cancer treatment

Synergistic effect of immune checkpoint blockade and anti-angiogenesis in cancer treatment

Abstract Immune checkpoint inhibitor (ICI) activates host’s anti-tumor immune response by blocking negative regulatory immune signals. A series of clinical trials showed that ICI could effectively induce tumor regression in a subset of advanced cancer patients. In clinical practice, a main concernin...

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Bibliographic Details
Main Authors: Ming Yi, Dechao Jiao, Shuang Qin, Qian Chu, Kongming Wu, Anping Li
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Molecular Cancer
Subjects:
Immune checkpoint inhibitor
PD-1
PD-L1
CTLA-4
VEGF
Anti-angiogenesis
Online Access:http://link.springer.com/article/10.1186/s12943-019-0974-6

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http://link.springer.com/article/10.1186/s12943-019-0974-6

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