Design, Modeling and Computational Analysis of crRNA to Regulate MetastamiR-10b and MetastamiR-126 in Post-transcriptional Level by CRISPR-C2c2 (Cas13a) Technique

Introduction: Metastasis is one the most important causes of mortality in cancer patients. Recent studies have shown the metastatic potential of a specific group of microRNAs called metastamirs.  miR-126 is shown to be correlated with the colorectal liver metastasis. Also, overexpression of miR-10b...

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Bibliographic Details
Main Authors: Fatemeh Ebrahimi Tarki, Mahsa Bourbour, Mahboobe Zarrabi
Format: Article
Language:fas
Published: Kerman University of Medical Sciences 2020-03-01
Series:مجله انفورماتیک سلامت و زیست پزشکی
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Online Access:http://jhbmi.ir/article-1-390-en.html