Regulatory roles of SP-A and exosomes in pneumonia-induced acute lung and kidney injuries

Regulatory roles of SP-A and exosomes in pneumonia-induced acute lung and kidney injuries

IntroductionPneumonia-induced sepsis can cause multiple organ dysfunction including acute lung and kidney injury (ALI and AKI). Surfactant protein A (SP-A), a critical innate immune molecule, is expressed in the lung and kidney. Extracellular vesicles like exosomes are involved in the processes of p...

Full description

Bibliographic Details
Main Authors: Xinghua Chen, Junping Guo, Salma Mahmoud, Gautam Vanga, Tianyi Liu, Wanwen Xu, Yunhe Xiong, Weichuan Xiong, Osama Abdel-Razek, Guirong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
acute kidney injury (AKI)
exosomes
innate immunity
renal tubular epithelial cells
surfactant protein A (SP-A)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1188023/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1188023/full

Similar Items