Sustained delivery of rhMG53 promotes diabetic wound healing and hair follicle development

Sustained delivery of rhMG53 promotes diabetic wound healing and hair follicle development

MG53 is an essential component of the cell membrane repair machinery, participating in the healing of dermal wounds. Here we develop a novel delivery system using recombinant human MG53 (rhMG53) protein and a reactive oxygen species (ROS)-scavenging gel to treat diabetic wounds. Mice with ablation o...

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Bibliographic Details
Main Authors: Hong Niu, Haichang Li, Ya Guan, Xin Zhou, Zhongguang Li, Serana Li Zhao, Peng Chen, Tao Tan, Hua Zhu, Valerie Bergdall, Xuehong Xu, Jianjie Ma, Jianjun Guan
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-12-01
Series:Bioactive Materials
Subjects:
Diabetic wound healing
hair follicle stem cell
MG53
ROS-Scavenging hydrogel
Controlled drug delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X22001347

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http://www.sciencedirect.com/science/article/pii/S2452199X22001347

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