Molecular Characterization of Somatic Alterations in Dukes’ B and C Colorectal Cancers by Targeted Sequencing

Molecular Characterization of Somatic Alterations in Dukes’ B and C Colorectal Cancers by Targeted Sequencing

Despite global progress in research, improved screening and refined treatment strategies, colorectal cancer (CRC) remains as the third most common malignancy. As each type of cancer is different and exhibits unique alteration patterns, identifying and characterizing gene alterations in CRC that may...

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Bibliographic Details
Main Authors: Shafina-Nadiawati Abdul, Nurul-Syakima Ab Mutalib, Khor S. Sean, Saiful E. Syafruddin, Muhiddin Ishak, Ismail Sagap, Luqman Mazlan, Isa M. Rose, Nadiah Abu, Norfilza M. Mokhtar, Rahman Jamal
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Pharmacology
Subjects:
colorectal cancer
next generation sequencing
Ion Ampliseq Comprehensive Cancer Panel
APC
SYNE1
precision medicine
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00465/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00465/full

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