Enduring disruption of reward and stress circuit activities by early-life adversity in male rats
Abstract In humans, early-life adversity (ELA) such as trauma, poverty, and chaotic environment is linked to increased risk of later-life emotional disorders including depression and substance abuse. These disorders involve underlying disruption of reward circuits and likely vary by sex. Accordingly...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-06-01
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Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-022-01988-w |