Direct assessment of nitrative stress in lipid environments: Applications of a designer lipid-based biosensor for peroxynitrite

Direct assessment of nitrative stress in lipid environments: Applications of a designer lipid-based biosensor for peroxynitrite

Summary: Lipid membranes and lipid-rich organelles are targets of peroxynitrite (ONOO−), a highly reactive species generated under nitrative stress. We report a membrane-localized phospholipid (DPPC-TC-ONOO–) that allows the detection of ONOO− in diverse lipid environments: biomimetic vesicles, mamm...

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Bibliographic Details
Main Authors: Bryan Gutierrez, Tushar Aggarwal, Huseyin Erguven, M. Rhia L. Stone, Changjiang Guo, Alyssa Bellomo, Elena Abramova, Emily R. Stevenson, Debra L. Laskin, Andrew J. Gow, Enver Cagri Izgu
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:iScience
Subjects:
Analytical chemistry
Biotechnology
Membranes
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223026445

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223026445

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