Activation of the urotensin-II receptor by remdesivir induces cardiomyocyte dysfunction
Abstract Remdesivir is an antiviral drug used for COVID-19 treatment worldwide. Cardiovascular side effects have been associated with remdesivir; however, the underlying molecular mechanism remains unknown. Here, we performed a large-scale G-protein-coupled receptor screening in combination with str...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-05-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-023-04888-x |