Multifunctional Protein A Is the Only Viral Protein Required for Nodavirus RNA Replication Crown Formation

Multifunctional Protein A Is the Only Viral Protein Required for Nodavirus RNA Replication Crown Formation

Positive-strand RNA virus RNA genome replication occurs in membrane-associated RNA replication complexes (RCs). Nodavirus RCs are outer mitochondrial membrane invaginations whose necked openings to the cytosol are “crowned” by a 12-fold symmetrical proteinaceous ring that functions as the main engin...

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Bibliographic Details
Main Authors: Johan A. den Boon, Hong Zhan, Nuruddin Unchwaniwala, Mark Horswill, Kailey Slavik, Janice Pennington, Amanda Navine, Paul Ahlquist
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Viruses
Subjects:
positive-strand RNA virus
nodavirus
RNA replication complex
cryo-EM tomography
crown complex
Online Access:https://www.mdpi.com/1999-4915/14/12/2711

Internet

https://www.mdpi.com/1999-4915/14/12/2711

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