Factors Affecting the Pharmacology of Antibody–Drug Conjugates

Factors Affecting the Pharmacology of Antibody–Drug Conjugates

Major advances in therapeutic proteins, including antibody–drug conjugates (ADCs), have created revolutionary drug delivery systems in cancer over the past decade. While these immunoconjugate agents provide several advantages compared to their small-molecule counterparts, their clinical use is still...

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Bibliographic Details
Main Authors: Andrew T. Lucas, Lauren S. L. Price, Allison N. Schorzman, Mallory Storrie, Joseph A. Piscitelli, Juan Razo, William C. Zamboni
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Antibodies
Subjects:
antibody–drug conjugates
mononuclear phagocyte system
pharmacokinetics
pharmacology
therapeutic proteins
Online Access:http://www.mdpi.com/2073-4468/7/1/10

Internet

http://www.mdpi.com/2073-4468/7/1/10

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