Antigen-specific B cells reactivate an effective cytotoxic T cell response against phagocytosed Salmonella through cross-presentation.
BACKGROUND: The eradication of facultative intracellular bacterial pathogens, like Salmonella typhi, requires the concerted action of both the humoral immune response and the cytotoxic CD8(+) T cell response. Dendritic cells (DCs) are considered to orchestrate the cytotoxic CD8(+) T cell response vi...
Hlavní autoři: | , , , , , , |
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Médium: | Článek |
Jazyk: | English |
Vydáno: |
Public Library of Science (PLoS)
2010-01-01
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Edice: | PLoS ONE |
On-line přístup: | http://europepmc.org/articles/PMC2946406?pdf=render |