Betulin and Crinum asiaticum L. bulbs extract attenuate pulmonary fibrosis by down regulating pro-fibrotic and pro-inflammatory cytokines in bleomycin-induced fibrosis mice model

Background: Pulmonary fibrosis (PF) is a lung disease characterized by scaring of lung tissue that impairs lung functions. The estimated survival time of patients with pulmonary fibrosis is 3–5 years. Bleomycin (BLM) is used clinically in the treatment of Hodgkin lymphoma and testicular germ-cell tu...

Full description

Bibliographic Details
Main Authors: Michael Ofori, Cynthia Amaning Danquah, Joshua Asante, Selase Ativui, Peace Doe, Alhassan Abdul-Nasir Taribabu, Isaac Newton Nugbemado, Adwoa Nkrumah Mensah
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Heliyon
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402304121X