ASCL2 Affects the Efficacy of Immunotherapy in Colon Adenocarcinoma Based on Single-Cell RNA Sequencing Analysis

ASCL2 Affects the Efficacy of Immunotherapy in Colon Adenocarcinoma Based on Single-Cell RNA Sequencing Analysis

Colon adenocarcinoma (COAD) is one of the leading causes of cancer-associated deaths worldwide. Patients with microsatellite instability-high (MSI-H) tumors were shown to highly benefit from immune checkpoint inhibitors (ICIs) than patients with microsatellite stable (MSS) tumors. Furthermore, the i...

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Bibliographic Details
Main Authors: Lei Wu, Shengnan Sun, Fei Qu, Xiuxiu Liu, Meili Sun, Ying Pan, Yan Zheng, Guohai Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
colon adenocarcinoma
single-cell RNA-seq
microsatellite stable
microsatellite instability-high
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.829640/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.829640/full

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