IRES-mediated translation of utrophin A is enhanced by glucocorticoid treatment in skeletal muscle cells.

Glucocorticoids are currently the only drug treatment recognized to benefit Duchenne muscular dystrophy (DMD) patients. The nature of the mechanisms underlying the beneficial effects remains incompletely understood but may involve an increase in the expression of utrophin. Here, we show that treatme...

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Váldodahkkit: Pedro Miura, Meghan Andrews, Martin Holcik, Bernard J Jasmin
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Public Library of Science (PLoS) 2008-01-01
Ráidu:PLoS ONE
Liŋkkat:http://europepmc.org/articles/PMC2396518?pdf=render