Composition of ex vivo perfusion solutions and kinetics define differential cytokine/chemokine secretion in a porcine cardiac arrest model of lung preservation

BackgroundEx vivo lung perfusion (EVLP) uses continuous normothermic perfusion to reduce ischemic damage and to improve post-transplant outcomes, specifically for marginal donor lungs after the donation after circulatory death. Despite major efforts, the optimal perfusion protocol and the compositio...

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Bibliographic Details
Main Authors: Lena Radomsky, Achim Koch, Carolin Olbertz, Yongjie Liu, Kerstin Beushausen, Jana Keil, Ursula Rauen, Christine S. Falk, Jenny F. Kühne, Markus Kamler
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1245618/full