Alkaloids of <i>Dicranostigma franchetianum</i> (Papaveraceae) and Berberine Derivatives as a New Class of Antimycobacterial Agents

Alkaloids of <i>Dicranostigma franchetianum</i> (Papaveraceae) and Berberine Derivatives as a New Class of Antimycobacterial Agents

Tuberculosis (TB) is a widespread infectious disease caused by <i>Mycobacterium tuberculosis</i>. The increasing incidence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains has created a need for new antiTB agents with new chemical scaffolds to combat the disease....

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Bibliographic Details
Main Authors: Viriyanata Wijaya, Ondřej Janďourek, Jana Křoustková, Kateřina Hradiská-Breiterová, Jan Korábečný, Kateřina Sobolová, Eliška Kohelová, Anna Hošťálková, Klára Konečná, Marcela Šafratová, Rudolf Vrabec, Jiří Kuneš, Lubomír Opletal, Jakub Chlebek, Lucie Cahlíková
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Biomolecules
Subjects:
<i>Dicranostigma franchetianum</i>
Papaveraceae
isoquinoline alkaloids
berberine
antimycobacterial activity
cytotoxicity
Online Access:https://www.mdpi.com/2218-273X/12/6/844

Internet

https://www.mdpi.com/2218-273X/12/6/844

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