TrkA inhibition alleviates bladder overactivity in cyclophosphamide-induced cystitis by targeting hyperpolarization-activated cyclic nucleotide-gated channels

Objective(s): To investigate the potential of Tropomyosin receptor kinase A (TrkA) for the treatment of interstitial cystitis/ bladder pain syndrome (IC/BPS).Materials and Methods: Sixty-four female rats were randomly assigned to the control and cyclophosphamide (CYP) groups. Quantitative reverse tr...

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Bibliographic Details
Main Authors: Qian Liu, Xiaodong Li, Jingzhen Zhu, Bishao Sun, Shadan Li
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-06-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_22166_a71978137de83c1fa1f3258b368aa945.pdf