IDARUCIZUMAB, A SPECIFIC REVERSAL AGENT FOR DABIGATRAN: THE PRESENT-DAY KNOWLEDGE

Idaruzizumab (Praxbind©) is a specific reversal agent for dabigatran, which is a humanized Fab fragment of a monoclonal antibody. Immediately after administration, the drug binds to dabigatran and its metabolites, inhibiting 99% of the anti-coagulant activity of dabigatran from the very first minute...

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Bibliographic Details
Main Author: Olga O. Shakhmatova
Format: Article
Language:Russian
Published: «REMEDIUM GROUP» Ltd. 2018-12-01
Series:Атеротромбоз
Subjects:
Online Access:https://www.aterotromboz.ru/jour/article/view/176