Improved Real-Time Quaking Induced Conversion for Early Diagnostics of Creutzfeldt–Jakob Disease in Denmark

Improved Real-Time Quaking Induced Conversion for Early Diagnostics of Creutzfeldt–Jakob Disease in Denmark

Cerebrospinal fluid-based real-time quaking-induced conversion (CSF RT-QuIC) is currently the most prominent method for early detection of sporadic Creutzfeldt–Jakob disease (sCJD), the most common prion disease. CSF RT-QuIC delivers high sensitivity (>90%) and specificity (100%), which has been...

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Bibliographic Details
Main Authors: Remarh Bsoul, Eva Løbner Lund, Kimberley Burns, Mary Andrews, Neil McKenzie, Alison Green, Aušrinė Areškevičiūtė
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
Creutzfeldt–Jakob disease—CJD
improved real-time quaking-induced conversion—IQ
RT-QuIC
cerebrospinal fluid—CSF
prions
prion disease
Online Access:https://www.mdpi.com/1422-0067/24/7/6098

Internet

https://www.mdpi.com/1422-0067/24/7/6098

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