Suppression of autophagy through JAK2/STAT3 contributes to the therapeutic action of rhynchophylline on asthma

Suppression of autophagy through JAK2/STAT3 contributes to the therapeutic action of rhynchophylline on asthma

Abstract Background Asthma is a chronic inflammatory disease characterized by airway remodeling and inflammation. Rhynchophylline is a kind of indole alkaloid isolated from Uncaria rhynchophylla. Here we investigated the effect of rhynchophylline on autophagy in asthma. Methods A mice model of asthm...

Full description

Bibliographic Details
Main Authors: Hui Li, Qianyu Bi, Hongxia Cui, Chuanfeng Lv, Meng Wang
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Autophagy
Asthma
Rhynchophylline
JAK2
STAT3
Online Access:https://doi.org/10.1186/s12906-020-03187-w

Internet

https://doi.org/10.1186/s12906-020-03187-w

Similar Items