SARS-CoV-2-Specific CD8<sup>+</sup> T-Cells in Blood but Not in the Lungs of Vaccinated K18-hACE2 Mice after Infection

SARS-CoV-2-Specific CD8<sup>+</sup> T-Cells in Blood but Not in the Lungs of Vaccinated K18-hACE2 Mice after Infection

Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 enters the host by infecting nasal ciliated cells. Then, the virus can spread towards the oropharyngeal cavity and the pulmonary tissues. The antiviral adaptive immunity is promptly induced in response to the virus’s detection, with virus-sp...

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Bibliographic Details
Main Authors: Flavia Ferrantelli, Francesco Manfredi, Chiara Chiozzini, Patrizia Leone, Katherina Pugliese, Massimo Spada, Antonio Di Virgilio, Andrea Giovannelli, Mauro Valeri, Andrea Cara, Zuleika Michelini, Mauro Andreotti, Maurizio Federico
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Vaccines
Subjects:
SARS-CoV-2
CD8<sup>+</sup> T-cell immunity
vaccines
K18 transgenic mice
Online Access:https://www.mdpi.com/2076-393X/11/9/1433

Internet

https://www.mdpi.com/2076-393X/11/9/1433

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